AI clinical trial finder / Breast cancer

AI clinical trials in breast cancer: open or opening soon

99 studies that use artificial intelligence or machine learning and are recruiting or about to recruit, from ClinicalTrials.gov (updated 2026-11-05).

Before you contact a study: a listing here is not a recommendation. Check the eligibility criteria and contacts on the official ClinicalTrials.gov page, and discuss any trial with your own doctor. Taking part is voluntary, and you can usually leave a study at any time.

Most common countries with study sites

China (20)United States (20)France (7)Spain (7)Italy (5)Canada (4)South Korea (4)Turkey (Türkiye) (3)Norway (2)Greece (2)Lithuania (2)Sweden (2)Germany (2)Finland (1)United Kingdom (1)

Studies

Study	Status	Type	Countries	Start
Opportunistic Breast Cancer Screening Using Non-Contrast Chest CT NCT07557654 · Fudan University	Recruiting	Observational	China	2026-05
Artificial Intelligence Powered Digital Education Based on the Neuman Systems Model for Breast Cancer Patients Receiving Radiotherap NCT07649902 · Ataturk University	Not yet recruiting	Interventional	not listed	2026-11
Chatbot Utilization for Pedigree Creation and Cancer Risk Assessment in Cancer Genetic Counseling NCT07887620 · Roswell Park Cancer Institute	Recruiting	Interventional	United States	2026-11
Role of Artificial Intelligence in Breast Cancer Screening Via Mammography NCT07882420 · Centre Antoine Lacassagne	Not yet recruiting	Interventional	France	2027-01
Artificial Intelligence Integration in Breast Cancer Screening: The ANIHTA Study NCT07879937 · Fondazione Policlinico Universitario Agostino Gemelli IRCCS	Not yet recruiting	Observational	Italy	2026-11
Pre-Treatment Breast DCE-MRI AI Model to Predict Neoadjuvant Chemotherapy Benefit in Locally Advanced Triple-Negative Breast Cancer NCT07880600 · Fujian Cancer Hospital	Recruiting	Observational	China	2026-10
De-EscaLaTion of Aromatase Inhibitor Therapy: A Randomized Phase II Study of De-escalated Letrozole in Hormone Receptor-Positive Early Breast Cancer NCT07866430 · Montefiore Medical Center	Not yet recruiting	Interventional · Phase 2	United States	2026-09
Benchmarking Large Language Models Against Tumour Boards for Oncology Treatment Recommendations NCT07739121 · Assistance Publique - Hôpitaux de Paris	Recruiting	Observational	France	2026-05
Ataraxis Real-World Clinical Outcomes Registry Linking AI-Based Pathology Scores to Patient Outcomes NCT07706842 · Ataraxis AI, Inc.	Not yet recruiting	Observational	not listed	2026-10
Emergence of Predictive Metabolomic Biomarkers of Response to Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer. NCT07847398 · Centre Antoine Lacassagne	Not yet recruiting	Interventional	France	2026-10
Non-Invasive Artificial Intelligence-Based Platform MonIToring Program (NIP IT!) NCT05196087 · University Health Network, Toronto	Recruiting	Observational	Canada	2022-07
Artificial Intelligence (AI)-Based Personalized Exercise Coaching for Patients With Breast Cancer NCT07844941 · Shanghai Jiao Tong University School of Medicine	Recruiting	Interventional	China	2026-07
AI-Based Phenome Data Analysis for Predicting the Onset of Major Diseases NCT07595718 · Jae Yong Jeon, MD	Recruiting	Observational	South Korea	2026-04
AI-Based Symptom Management for Post-Treatment Breast Cancer Survivors NCT07770243 · Hong Kong Metropolitan University	Not yet recruiting	Interventional	not listed	2026-09
Identifying Patterns in the Breath of Individuals With Breast Cancer NCT06512350 · Breathe BioMedical Inc	Recruiting	Observational	Canada, United States	2025-02
Artificial Intelligence-supported Mobile Application for Patients With Breast Cancer NCT07826338 · Ege University	Recruiting	Interventional	Turkey (Türkiye)	2026-06
ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE) - iSono Health NCT07505797 · iSono Health, Inc.	Recruiting	Observational	United States	2025-12
A Preregistered Multi-Cohort Evaluation of the FATHOM AI System for Molecular Testing Prioritization to Support Clinical Trial Enrollment NCT07814872 · Harvard Medical School (HMS and HSDM)	Not yet recruiting	Observational	United States	2026-09
A Prospective Study to Develop and Clinically Validate an in Vitro Diagnostic Medical Device That Uses Blood to Classify Patients at High Risk for Breast Cancer NCT06672302 · EXoPERT	Recruiting	Observational	South Korea, United States	2024-10
CT-AI Breast Cancer Opportunistic Screening Health Examination Study NCT07809698 · The First Affiliated Hospital with Nanjing Medical University	Not yet recruiting	Interventional	not listed	2026-09
A Study of T-DXd in AI-Assessed HER2-Ultralow Metastatic Breast Cancer NCT07782086 · Shuangyue Liu	Not yet recruiting	Interventional	China	2026-09
Application of CT-Linac-Based "All-in-One" One-Stop Radiotherapy in Breast Cancer NCT07776301 · Fudan University	Recruiting	Interventional	China	2021-08
Research on the Development and Validation of Personalized Exercise Prescription System for Breast Cancer Patients Based on Large Language Models NCT07767565 · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Not yet recruiting	Observational	China	2026-09
TRUST-ACE - Anticancer-treatment Cardiotoxicity Identification by Echocardiography NCT06310330 · Norwegian University of Science and Technology	Recruiting	Interventional	Norway	2024-03
A Prospective Multicenter Study of the TuFEst-LN Model for Axillary Lymph Node Status Assessment in Breast Cancer NCT07304934 · Second Affiliated Hospital, Zhejiang University, School of Medicine	Recruiting	Observational	China	2025-08
Generative AI Patient Education Module for Breast Oncology NCT07512271 · University of California, San Francisco	Recruiting	Interventional	United States	2026-07
Study on Female Patients' Mammographic Texture Features NCT06469606 · Tampere University Hospital	Recruiting	Interventional	Finland	2024-06
Intra-operative Detection of Positive Margins and Lymph Nodes in Breast Surgery NCT06977698 · University of Nottingham	Recruiting	Observational	United Kingdom	2023-10
Screening Tool Artificial Intelligence-based for Predicting the Genetic Risk of BREAST Cancer NCT07070128 · AstraZeneca	Recruiting	Observational	Brazil	2025-08
Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry NCT07732686 · University of Oklahoma	Not yet recruiting	Observational	United States	2026-10
Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial NCT06184750 · National Cancer Institute (NCI)	Recruiting	Interventional · Phase 2	United States	2024-09
Pre-Treatment DCE-MRI AI Models Predict Neoadjuvant Chemotherapy Response in HR+/HER2- Breast Cancer NCT07702708 · Fujian Cancer Hospital	Recruiting	Observational	China	2026-06
Artificial Intelligence Model-Guided Neoadjuvant Anti-HER2 Targeted Therapy NCT07528716 · Fudan University	Recruiting	Interventional · Phase 3	China	2026-05
Fluorocholine PET/MR in Breast Cancer NCT07587086 · Taipei Veterans General Hospital, Taiwan	Recruiting	Observational	Taiwan	2022-06
EXoPERT EMERALD Clinical Study NCT07186296 · EXoPERT	Recruiting	Observational	United States	2025-05
Prediction of Neoadjuvant Therapy Efficacy and Prognosis for Breast Cancer Based on Multimodal Data NCT07671690 · Yunnan Cancer Hospital	Not yet recruiting	Interventional	not listed	2026-06
MELIORA Virtual Coach Intervention for Breast Cancer Prevention NCT07200427 · Harokopio University	Recruiting	Interventional	Greece, Lithuania, Spain, Sweden	2026-03
Evaluating an AI-Based Mobile Application for Chemotherapy Support in Breast Cancer Patients NCT07273812 · Dena h. Al-Tameemi	Recruiting	Interventional	Iraq	2026-06
Non-Contrast Breast MRI Diagnosis and Risk Stratification Using DWI-Generated Synthetic Contrast Enhancement NCT07598084 · Peking University People's Hospital	Not yet recruiting	Observational	not listed	2026-06
Research on the Whole-Process Intelligent Diagnosis and Treatment of Digital Breast Tomosynthesis Based on Deep Learning NCT07605195 · Yunnan Cancer Hospital	Not yet recruiting	Interventional	not listed	2026-05
Arm Swelling Occurence in Breast Cancer Patients With Nodal Radiotherapy: Impact of Informing Them of AI-predicted Risk NCT07187726 · UNICANCER	Recruiting	Interventional	France, Netherlands	2025-10
LEARN: Learning Environment for Artificial Intelligence in Radiotherapy New Technology NCT05184790 · University of Sydney	Recruiting	Observational	Australia	2023-02
Identification of Breast Cancer in Breath Samples Using Trained Detection Dogs NCT07038785 · SpotitEarly	Recruiting	Observational	Israel, United States	2025-07
A Clinical Investigation to Confirm the Ability of MammoWave in Breast Lesions Detection NCT05300464 · Umbria Bioengineering Technologies	Recruiting	Interventional	Italy, Spain	2023-01
Preventing Breast Cancer Therapy-related Cardiovascular Toxicity With a Daily-adapted Program With Mhealth Support NCT06518200 · Universidad de Granada	Not yet recruiting	Interventional	Spain	2026-09
Remote Monitoring and Symptom Management Digital Application NCT07553572 · Patrick C. Johnson, MD	Recruiting	Interventional	United States	2026-04
Intraoperative Margin Assessment in Breast Cancer With HSI-Raman NCT07111728 · Istituti Clinici Scientifici Maugeri SpA	Recruiting	Observational	Italy	2025-10
AI-Assisted Chemotherapy Side Effect Management NCT07198581 · Incheon St.Mary's Hospital	Recruiting	Interventional	South Korea	2025-11
Artificial Intelligence and Machine Learning to Guide CDK4/6 Inhibitor Rechallenge in Breast Cancer. NCT07227233 · University of California, San Diego	Recruiting	Interventional · Phase 2	United States	2026-03
Screening Mammography: Single Reading by One Radiologist With AI vs. Double Reading by Two Radiologists (AI-BCSQ) NCT07075679 · University Hospital Olomouc	Recruiting	Interventional	Czechia	2025-10
Deep Learning for Musculoskeletal Complications in Breast Cancer NCT07236658 · Ankara Etlik City Hospital	Recruiting	Observational	Turkey (Türkiye)	2025-07
Construction of a Benchmark for Breast Ultrasound AI Interpretation and Performance Evaluation of Multimodal AI Models NCT07500428 · Peking Union Medical College Hospital	Recruiting	Observational	China	2026-03
Prospective Validation of Ataraxis AI Test for Predicting Treatment Response in Neoadjuvant Breast Cancer NCT07327970 · Young-Joon Kang	Recruiting	Observational	South Korea	2026-01
Screening for Brain Metastases NCT07492121 · University of Zurich	Not yet recruiting	Interventional · Phase 2	Switzerland	2026-09
Wide-Angle Tomosynthesis and AI in Diagnostic Mammography NCT07491055 · Jean Seely	Not yet recruiting	Observational	not listed	2026-04
ML Score Prediction of Cardiotoxicity in Cancer Patients Receiving Anthracycline Chemotherapy or HER2-Targeted Therapies NCT07191730 · University Hospital, Caen	Recruiting	Observational	France	2025-10
Clinical Translation Research on a Multi-omics Breast Cancer Distant Metastasis Prediction Model Empowered by Artificial Intelligence NCT07252986 · Second Affiliated Hospital, Zhejiang University, School of Medicine	Recruiting	Observational	China	2025-12
Safe and Explainable AI NCT06694181 · Abramson Cancer Center at Penn Medicine	Recruiting	Observational	United States	2025-11
Prospective Ultrasound Data Collection Study for AI-Based Detection of Breast Biopsy Markers NCT07427407 · AURA Health Technologies	Not yet recruiting	Observational	United States	2026-05
A Study on Predicting the Risk of Distant Metastasis in Breast Cancer Using AI-Generated Spatial Pathological Maps NCT07244094 · Second Affiliated Hospital, Zhejiang University, School of Medicine	Recruiting	Observational	China	2025-11
AI-Enhanced Imaging in Population Breast Cancer Screening NCT07411443 · Fudan University	Recruiting	Interventional	China	2025-01
Application of Multimodal MRI-based Radiomics in Histological Grading and Prognostic Assessment of Breast Cancer NCT07389200 · Hao Xu	Not yet recruiting	Observational	not listed	2028-01
Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses NCT06171607 · University of Southern California	Recruiting	Interventional · Phase 1	United States	2020-11
Validation of the Oncoliq Test for the Early Detection of Breast Cancer. NCT07331506 · Oncoliq US Inc	Recruiting	Observational	Argentina	2025-10
Artificial Intelligence in Mammography Screening in Norway NCT06032390 · Norwegian Institute of Public Health	Recruiting	Interventional	Norway	2024-11
Precision Physical Exercise for Personalized Onco-Hematology. NCT07286539 · University of Salamanca	Not yet recruiting	Interventional	not listed	2026-04
TRIple Negative Breast Cancer Markers In Liquid Biopsies Using Artificial Intelligence NCT04874064 · Jewish General Hospital	Recruiting	Observational	Canada	2019-12
A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients NCT06934239 · Jonsson Comprehensive Cancer Center	Recruiting	Interventional · Phase 4	United States	2025-10
Low Dose Exemestane vs Low Dose Tamoxifen in Post-menopausal Women at High Risk for Breast Cancer. NCT06364267 · Andrea DeCensi	Recruiting	Interventional · Phase 2	Italy	2025-10
Mirai-MRI: Validation of AI Models for Breast Cancer Risk NCT07121972 · University of California, San Francisco	Recruiting	Interventional	United States	2025-11
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry NCT03452774 · Massive Bio, Inc.	Recruiting	Observational	Puerto Rico, United States	2018-01
UCF MammoChat: Image Repository NCT07214883 · University of Central Florida	Recruiting	Observational	United States	2025-09
AI-Based Self-Supervised Learning Model Using Non-Contrast Breast MRI for Early Screening and Clinical Utility Evaluation NCT07205276 · Second Affiliated Hospital, Zhejiang University, School of Medicine	Not yet recruiting	Interventional	not listed	2025-10
Web-based Intervention for Long-term Breast Cancer Survivors NCT05322460 · Cristina García-Vivar	Recruiting	Interventional	Spain	2023-12
MELIORA Data Collection Campaigns NCT07190066 · Harokopio University	Recruiting	Interventional	Greece, Lithuania, Spain, Sweden	2025-04
AI-based pCR Assessment/Prediction in HER2-Positive BC Using PET/MRI NCT06708910 · Heinrich-Heine University, Duesseldorf	Recruiting	Observational	Germany	2025-07
Optimizing and Personalising Azacitidine Combination Therapy for Treating Solid Tumours QPOP and CURATE.AI NCT05381038 · National University Hospital, Singapore	Recruiting	Interventional · Phase 1, Phase 2	Singapore	2023-02
Intraoperative Detection of Breast Cancer by Electrosurgical Gas Analysis and Artificial Intelligence NCT07131735 · Pontificia Universidad Catolica de Chile	Recruiting	Observational	Chile	2023-12
Artificial Intelligence Model-Assisted Accurate Diagnosis of Early-Stage Breast Cancer NCT07063667 · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	Not yet recruiting	Observational	China	2025-08
Human-AI Collaborative INSIGHT Diagnostic Workflow for in Breast Cancer With Extensive Intraductal Component NCT07060599 · Sun Yat-sen University	Not yet recruiting	Interventional	China	2025-08
A Phase II Clinical Trial of Artificial Intelligence-assisted One-stop Radiotherapy for Breast Cancer After Breast-conserving Surgery NCT06686459 · Sun Yat-sen University	Recruiting	Interventional	China	2025-04
Effect of Cryotherapy in the Prevention of Madarosis Produced by Chemotherapy in Breast Cancer Patients NCT06955702 · University of Salamanca	Recruiting	Interventional	Spain	2023-11
Reflects the Intervention (AI Chatbot) NCT06943911 · Mostafa Shaban	Not yet recruiting	Interventional	Egypt	2025-04
Assessment of the Breast Cosmesis Using Deep Neural Networks: an Exploratory Study (ABCD) NCT05450016 · Tata Memorial Centre	Recruiting	Observational	India	2021-10
Analysis of Circulating Tumor Markers in Blood NCT04025541 · Institut du Cancer de Montpellier - Val d'Aurelle	Recruiting	Interventional	France	2018-05
The Impact of AI- Supported Education in Mastectomy Patient NCT06796166 · Bezmialem Vakif University	Recruiting	Interventional	Turkey (Türkiye)	2024-08
Precision Retrospective Integrative Study for Metastatic Lymph Nodes in Breast Cancer NCT06738459 · Centro di Riferimento Oncologico - Aviano	Recruiting	Observational	Austria, Italy	2025-01
AI Model for Classifying Breast Cancer From Histopathology Images NCT06717984 · Taufiq Hasan, PhD	Recruiting	Observational	Bangladesh	2024-01
The Impact of Radiotherapy on Oligometastatic Cancer NCT05933876 · Institut Investigacio Sanitaria Pere Virgili	Recruiting	Observational	Spain	2022-12
Prospective Validation and Application of an Artificial Intelligence-based Model for Evaluating the Efficacy of Breast Cancer Patients After Neoadjuvant Therapy NCT06649565 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences	Recruiting	Observational	China	2024-01
AI-Assisted Non-Contrast CT for Multi-Cancer Screening NCT06632886 · Guo ShiWei	Recruiting	Interventional	China	2024-10
Diagnostic Performance of Breast Cancer Screening Second Reading Process Assisted by AI NCT05800132 · Therapixel	Recruiting	Interventional	France	2023-06
The MARVIN Chatbots to Provide Information for Different Health Conditions NCT05789901 · McGill University Health Centre/Research Institute of the McGill University Health Centre	Recruiting	Interventional	Canada	2024-03
AI-Assisted System for Accurate Diagnosis and Prognosis of Breast Phyllodes Tumors NCT06286267 · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Recruiting	Observational	China	2023-03
Stockholm Mammography Risk Stratified Trial NCT06270355 · Karolinska Institutet	Not yet recruiting	Interventional · Phase 3	not listed	2024-04
ThermoBreast - Non-contact Breast Cancer Imaging Using AI-enhanced Thermography. NCT06266026 · ThermoMind Ltd.	Recruiting	Interventional	Germany	2023-12
Intelligent Remote Intervention for High-risk Breast Cancer Populations NCT06193707 · Qianfoshan Hospital	Not yet recruiting	Interventional	not listed	2024-01
Hypo Versus Conventional Fractionation in Reconstructed-Breast Cancer Mastectomy Patients NCT05253170 · Seoul National University Bundang Hospital	Not yet recruiting	Interventional · Phase 3	not listed	2022-04
Nomogram to Predict Breast Cancer Related Lymphedema NCT04665882 · Wuhan University	Recruiting	Interventional	China	2020-12

Full, filterable list: search ClinicalTrials.gov.

How to use this list

Open a study to see who can take part (age, diagnosis, previous treatment) and the contact details of the study team.
Interventional studies test a tool or treatment; observational studies collect data, for example to develop or check an AI model.
Phase applies to medicines; many AI and device studies show "not applicable".
Status, dates and titles are shown as the study sponsors registered them; check the study page for the latest status.
Ask your doctor whether a study fits your situation before you apply.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). Search: condition "Breast Cancer" with terms for artificial intelligence, machine learning, deep learning, large language model or neural network; status recruiting or not yet recruiting. Healthcare with AI is not involved in any of these studies.