AI clinical trial finder / Prostate cancer

AI clinical trials in prostate cancer: open or opening soon

61 studies that use artificial intelligence or machine learning and are recruiting or about to recruit, from ClinicalTrials.gov (updated 2026-11-05).

Before you contact a study: a listing here is not a recommendation. Check the eligibility criteria and contacts on the official ClinicalTrials.gov page, and discuss any trial with your own doctor. Taking part is voluntary, and you can usually leave a study at any time.

Most common countries with study sites

United States (16)China (16)Italy (5)France (5)United Kingdom (3)Hong Kong (2)Germany (2)Spain (2)Norway (2)Cyprus (2)Canada (2)Greece (1)Lithuania (1)Australia (1)Vietnam (1)

Studies

Study	Status	Type	Countries	Start
Artificial Intelligence (AI)-Assisted Risk-based Prostate Cancer Detection NCT05443412 · Chinese University of Hong Kong	Recruiting	Observational	Hong Kong	2023-08
To Evaluate an MRI-based Optimized Prostate Cancer Diagnostic Pathway Powered by Artificial Intelligence NCT06360523 · Chinese University of Hong Kong	Recruiting	Interventional	Hong Kong	2024-06
Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells NCT05691465 · National Cancer Institute (NCI)	Recruiting	Interventional · Phase 2	United States	2023-12
Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate NCT07888322 · Aristotle University Of Thessaloniki	Not yet recruiting	Observational	Germany, Greece, Italy, Spain	2026-10
Prostate Risk Or Radiology Assessment Non-inferiority Design, Upfront MRI or Risk Calculator in Men With Suspected Prostate Cancer NCT07422597 · Norwegian University of Science and Technology	Recruiting	Interventional	Norway	2026-03
Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer NCT03354416 · National Cancer Institute (NCI)	Recruiting	Observational	United States	2018-02
Artificial Intelligence Software (Prostate Intelligence) for Detecting Clinically Significant Prostate Cancer on MRI NCT07875491 · Fondazione Policlinico Universitario Agostino Gemelli IRCCS	Not yet recruiting	Interventional	Italy	2026-11
Benchmarking Large Language Models Against Tumour Boards for Oncology Treatment Recommendations NCT07739121 · Assistance Publique - Hôpitaux de Paris	Recruiting	Observational	France	2026-05
CascadeDiagnose Prostate MRI NCT07844304 · First Affiliated Hospital of Guangxi Medical University	Not yet recruiting	Observational	China	2026-10
Cancer Oriented Understanding and Navigation Via Supportive and Educational Language Models (COUNSEL) NCT07836933 · University of California, San Francisco	Not yet recruiting	Interventional	United States	2026-10
A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men NCT07126548 · Mayo Clinic	Recruiting	Interventional	United States	2026-04
AI Chatbot for Prostate Radiation Therapy Patient Education NCT07719062 · Brigham and Women's Hospital	Not yet recruiting	Interventional	not listed	2026-12
Artificial Intelligence to Personalize Prostate Cancer Treatment (the HypoElect Trial) NCT06582446 · German Oncology Center, Cyprus	Recruiting	Interventional · Phase 2	Cyprus	2024-09
Investigation of Impact of AI on Prostate Cancer Workflow NCT07084779 · Case Comprehensive Cancer Center	Recruiting	Interventional	United States	2025-09
Artificial Intelligence Driven Personalisation of Radiotherapy and Concomitant Androgen Deprivation Therapy for Prostate Cancer Patients (the HypoPro Trial) NCT06772441 · German Oncology Center, Cyprus	Recruiting	Interventional · Phase 2	Cyprus	2024-11
AI-Assisted Patient Support in mHSPC NCT07804030 · Fudan University	Not yet recruiting	Interventional	China	2026-09
MRI-Based Machine Learning Approach Versus Radiologist MRI Reading for the Detection of Prostate Cancer, The PRIMER Trial NCT07162194 · University of Southern California	Recruiting	Interventional	United States	2025-09
A Prospective Study Based on Spatial Multi-omics to Predict the Efficacy of ADT Combined With Second-generation Novel Hormonal Agents in Metastatic Hormone-sensitive Prostate Cancer. NCT07795177 · Anhui Medical University	Not yet recruiting	Interventional · Phase 2	China	2026-10
The PROSECCA Study, Answering New Questions in Prostate Cancer NCT06714630 · University of Edinburgh	Recruiting	Observational	United Kingdom	2024-07
AI Algorithm-Informed Biopsy for Prostate Cancer Detection With Indeterminate and Low-Risk Prostate MRI Lesions NCT07231627 · University of Arkansas	Recruiting	Interventional	United States	2026-06
miRNA Panel for PCa Diagnosis NCT07755592 · RenJi Hospital	Recruiting	Observational	China	2026-04
Development of an AI-Agent for Urological Disease Diagnosis and Treatment NCT07721935 · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Recruiting	Observational	China	2025-04
Large Language Model-Assisted cTNM Annotation From Chinese PSMA PET/CT Reports NCT07707232 · First Affiliated Hospital of Wenzhou Medical University	Recruiting	Observational	China	2026-06
Robotic Prostatectomy Artificial Intelligence Low Pressure Pain (RALP) Trial NCT06915909 · East and North Hertfordshire NHS Trust	Recruiting	Interventional	United Kingdom	2025-04
Integrating Quantitative MRI and Artificial Intelligence to Improve Prostate Cancer Classification NCT04765150 · Jonsson Comprehensive Cancer Center	Recruiting	Observational	United States	2021-04
Predictors of BCR After RARP for Localized Prostate Cancer: A Retrospective Analysis NCT07682584 · First Affiliated Hospital of Fujian Medical University	Not yet recruiting	Observational	not listed	2026-07
Prostate MRI Analysis by Radiologists and Artificial Intelligence - Disease Identification and Guided Management NCT07647445 · University College, London	Not yet recruiting	Interventional	not listed	2026-10
Phase II Randomized Trial of 2 Versus 5 Fraction Prostate Stereotactic Ablative Radiotherapy for Intermediate Risk Prostate Cancer NCT06835725 · British Columbia Cancer Agency	Recruiting	Interventional · Phase 2	Canada	2025-09
Artificial Intelligence (AI)-Enhanced Pretreatment Peer-review Process to Improve Patient Safety in Radiation Oncology NCT07463833 · UNC Lineberger Comprehensive Cancer Center	Recruiting	Interventional	United States	2026-06
Effects of Direct Artery Injection on Prostate Cancer Drug Delivery and Tumor Uptake: Imaging-Based Prediction of Treatment Effectiveness NCT07656337 · Lithuanian University of Health Sciences	Not yet recruiting	Interventional	Lithuania	2026-08
Multimodal Imaging and Digital Pathology for Prostate Cancer Prediction NCT07614256 · Guangxi Medical University	Recruiting	Observational	China	2025-05
LEARN: Learning Environment for Artificial Intelligence in Radiotherapy New Technology NCT05184790 · University of Sydney	Recruiting	Observational	Australia	2023-02
Improving Patient Understanding of Their Prostate Cancer Diagnosis Using AI NCT07040501 · Case Comprehensive Cancer Center	Not yet recruiting	Interventional	United States	2026-06
An International Multicenter Clinical Study on Application of UroMed AI Doctor Based on Large Language Models NCT07555756 · First Affiliated Hospital of Guangxi Medical University	Not yet recruiting	Interventional	China, Vietnam	2026-05
AI-based Measurements of Tumour Burden in PSMA PET-CT NCT06363435 · Elin Tragardh	Recruiting	Observational	Sweden	2024-03
Plasma Exosomal RNA Signature for Prostate Cancer Bone Metastasis NCT07553754 · Xijing Hospital	Recruiting	Observational	China	2026-03
Rezvilutamide With Radical Prostatectomy and Metastasis-Directed Therapy in Oligometastatic Prostate Cancer NCT07490210 · Fudan University	Not yet recruiting	Interventional · Phase 2	China	2026-05
PSMA-PET: Deep Radiomic Biomarkers of Progression and Response Prediction in Prostate Cancer NCT03594760 · Centre hospitalier de l'Université de Montréal (CHUM)	Recruiting	Interventional · Phase 3	Canada	2018-12
Screening and Staging of Benign vs Malignant Pelvic Abnormalities NCT07407959 · Mayo Clinic	Recruiting	Observational	United States	2025-09
Development and Prospective Validation of a Pathology-Based Artificial Intelligence Model for Predicting the Time to Castration Resistance of Prostate Cancer NCT07376057 · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Not yet recruiting	Observational	China	2026-01
The Development and Validation of MRI-AI-based Predictive Models for csPCa NCT06842264 · Peking University First Hospital	Recruiting	Observational	China	2024-01
Study of Predicting Lymph Node Metastasis of High-risk Prostate Cancer by Artificial Intelligence Multi-omics Analysis NCT07112599 · Anhui Medical University	Recruiting	Observational	China	2026-01
The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling NCT06717295 · Javier Toledo	Recruiting	Observational	Argentina, Nigeria, United Kingdom	2025-12
Community-Based Health Coach for Access to Germline Genetic Testing Among African American Men With Prostate Cancer NCT04763980 · University of California, San Francisco	Recruiting	Interventional	United States	2021-01
Prospective Evaluation of Imaging Response Biomarkers During [177Lu]Lu-PSMA in Metastatic Castration-resistant Prostate Cancer NCT06828263 · University Hospital, Grenoble	Recruiting	Observational	France	2023-08
RCT of NLP-Based Feedback for Improving SDM in Men With Localized Prostate Cancer NCT06856694 · Cedars-Sinai Medical Center	Recruiting	Interventional	United States	2025-10
Virtual Biopsy of Prostate Cancer Using PSMA PET and AI NCT07266129 · University Hospital of North Norway	Recruiting	Observational	Norway	2024-06
Application of Quantum Detection-Driven Artificial Intelligence Algorithms for Single-Molecule cfDNA Characterization in the Early Diagnosis of Prostate Cancer NCT07238959 · Shanghai Changzheng Hospital	Not yet recruiting	Observational	China	2025-12
Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer NCT06398639 · Adam S. Kibel, MD	Recruiting	Interventional	United States	2024-05
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry NCT03452774 · Massive Bio, Inc.	Recruiting	Observational	Puerto Rico, United States	2018-01
Comparison of MRI Artificial Intelligence-guided cTB Versus Routine cTB in Prostate Cancer Diagnosis NCT06392737 · Peking University First Hospital	Recruiting	Interventional	China	2024-05
Epidemiologic and Genetic Study on Familial Prostate Cancer NCT01221168 · Centre de Recherche sur les Pathologies Prostatiques	Recruiting	Observational	France	1996-10
Evaluation of the PROSTia Test in Patients Undergoing Prostate Biopsy NCT06931496 · Central Hospital, Nancy, France	Not yet recruiting	Interventional	France	2025-04
Impact of [18F] PSMA-1007 Imaging for Primary Staging of Prostate Cancer NCT06820333 · Heinrich-Heine University, Duesseldorf	Recruiting	Observational	Germany	2025-01
Artificial Intelligence-based Platform, Integrating Pathologic, Imaging and Molecular Profiles of Prostate Cancer NCT06468332 · Azienda Ospedaliero Universitaria Maggiore della Carita	Recruiting	Observational	Italy	2024-10
Validation of a Machine Learning Model Based on MR for the Prediction of Prostate Cancer NCT06773598 · IRCCS Azienda Ospedaliero-Universitaria di Bologna	Recruiting	Observational	Italy	2024-05
The Impact of Radiotherapy on Oligometastatic Cancer NCT05933876 · Institut Investigacio Sanitaria Pere Virgili	Recruiting	Observational	Spain	2022-12
Artificial Intelligence Models for Precision Prediction and Treatment of Prostate Cancer NCT06662708 · Shao Pengfei	Not yet recruiting	Interventional	China	2024-12
This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned. NCT05946824 · University of Rochester	Recruiting	Interventional · Phase 2	United States	2023-12
Artificial Intelligence 3D Augmented Reality Robot-Assisted-Radical- Prostatectomy v.s. no3D Intervention NCT06318559 · Fondazione del Piemonte per l'Oncologia	Recruiting	Interventional	Italy	2022-06
MRI Guided Radiotherapy and Radiobiological Data: the ISRAR Database (Irm Sequences for Radiobiological Adaptative Radiotherapy) NCT06041555 · Hospices Civils de Lyon	Recruiting	Observational	France	2024-01

Full, filterable list: search ClinicalTrials.gov.

How to use this list

Open a study to see who can take part (age, diagnosis, previous treatment) and the contact details of the study team.
Interventional studies test a tool or treatment; observational studies collect data, for example to develop or check an AI model.
Phase applies to medicines; many AI and device studies show "not applicable".
Status, dates and titles are shown as the study sponsors registered them; check the study page for the latest status.
Ask your doctor whether a study fits your situation before you apply.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). Search: condition "Prostate Cancer" with terms for artificial intelligence, machine learning, deep learning, large language model or neural network; status recruiting or not yet recruiting. Healthcare with AI is not involved in any of these studies.